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CORRInsights®: Increased Risk of Revision, Reoperation, and Implant Constraint in TKA After Multiligament Knee Surgery

Kim, Tae Kyun MD, PhD1,a

Clinical Orthopaedics and Related Research®: June 2017 - Volume 475 - Issue 6 - p 1627–1628
doi: 10.1007/s11999-017-5325-6
CORR Insights

1Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, 82 Gumi-ro 173 beon-gil, Bundang-gu, Seongnam, Republic of Korea

ae-mail;; e-mail;

Received January 31, 2017/Accepted March 16, 2017; previously published online March 23, 2017

This CORR Insights®is a commentary on the article ``Increased Risk of Revision, Reoperation, and Implant Constraint in TKA After Multiligament Knee Surgery” by Pancio and colleagues available at: DOI: 10.1007/s11999-017-5230-z.

The author certifies that neither he, nor any members of his immediate family, have any commercial associations (such as consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.

All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research® editors and board members are on file with the publication and can be viewed on request.

The opinions expressed are those of the writers, and do not reflect the opinion or policy of CORR® or The Association of Bone and Joint Surgeons®.

This CORR Insights® comment refers to the article available at DOI: 10.1007/s11999-017-5230-z.

This comment refers to the article available at:

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Where Are We Now?

In the current study, Pancio and colleagues performed a retrospective case-control analysis of TKAs done during a period of 19 years in patients with a history of multiligament knee surgery, and found that such patients had lower long-term implant survival, higher use of constrained TKA designs, higher risk of major complications (including reoperation and infection), and comparable scores for pain and function compared with similar patients undergoing TKA for primary osteoarthritis.

Although there is plenty of research examining patients who undergo TKA after ACL reconstruction [4, 8], few data are available regarding multiligament injuries. TKAs in patients who have undergone multiligament reconstruction are more challenging to perform, as these knees generally have additional scarring, poor soft-tissue integrity, bony and ligamentous deficiencies, retained hardware, or distorted anatomy [2]. Multiligament knee injuries are also associated with chondral injuries and meniscal tears [5, 6], increasing the propensity for early arthritis. The best surgical management approach for these patients is still up for debate [7, 9]. Surgical options to deal with chondral or meniscus injuries can be considered in conjunction with options for injured ligaments, however, multiple factors including patient age, expected activity levels, altered limb alignment, and degree of joint destruction should be discussed. Accordingly, TKA is sometimes the only plausible option for this difficult clinical scenario.

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Where Do We Need To Go?

A standardized operative treatment protocol for patients undergoing TKA after previous surgery for multiligament knee injury should be a priority. There is no consensus regarding when to use constrained prosthesis or what types of implants should be used. Additionally, the rehabilitation protocols for this patient population should be modified to include the increased prevalence of stiffness and decreased ROM associated with previous injuries and their surgical management [3]. However, there is no uniformity in the guidelines on such aspect with different surgeons following different approaches.

We are seeing an increase in high-velocity trauma injuries including multiligament knee injuries. How can the management of such multiligament knee injuries be streamlined and made uniform so as to avoid TKAs completely? If TKA does come into the picture, how can we refine our surgical techniques, including the use of constrained prosthesis designs for patients with posttraumatic arthritis, ensure longevity of the implant and reduce morbidity?

Pancio and colleagues found poorer implant survival, increased use of constrained designs, and more-frequent complications after TKA when comparing patients with history of multiligament knee surgery to those with primary osteoarthritis. However, they could not establish the reasons behind these differences. Therefore, further comprehensive research into the etiology of outcomes of TKA after multiligament knee surgery is needed. This becomes an even greater concern when one considers that a greater number of younger patients are presenting with TKA after previous knee surgery [1].

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How Do We Get There?

The next step is to define and formulate research studies that can clarify the reasons for relatively poor outcomes after TKA in patients with a history of multiligament knee surgery. Randomized prospective multicenter trials would provide a detailed analysis of TKA after multiligament knee surgeries. However, given the low incidence of these clinical scenarios, it will be difficult to launch randomized prospective studies by multiple centers. Therefore, nationwide database or retrospective studies with larger cohorts from multiple centers should be considered. Following the results of such studies, new guidelines and recommendations need to be given to maintain high-quality, evidence-based patient care. Orthopaedic surgeons should recognize that such cases need adequate and succinct clinical care, including improved surgical technique and better rehabilitation services, to enhance morbidity-free survival of this patient population.

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