Intraneural Lipoma of the Sciatic NerveCHIAO, HENRY, C.; MARKS, KENNETH, E.; BAUER, THOMAS, W.*; PFLANZE, WILLIAM**Clinical Orthopaedics and Related Research: August 1987 - Volume 221 - Issue - p 267–271 SECTION II GENERAL ORTHOPAEDICS: PDF Only Free Abstract Author InformationAuthors A large, well-encapsulated intraneural lipoma occurred within the sciatic nerve of a 34-year-old woman. In a review of the literature, significant differences were noted between the well-encapsulated and the diffusely infiltrative lipofibromatous hamartoma types of intraneural lipomas. The average age at the time of appearance of the well-encapsulated type is 45 years, with female predominance, while the infiltrative type arises in a younger age group (average age, eight years) with no sexual predominance. To avoid a recurrence, total excision is recommended in cases of the well-encapsulated type. Attempts to excise the diffusely infiltrative type are likely to fail. From the Departments of Orthopedic Surgery, Pathology,* and Radiology** of the Cleveland Clinic Foundation, Cleveland, Ohio. © Lippincott-Raven Publishers.