Case ReportsLocal Anesthetic and Steroidal Prostatic Injection for Chronic Pelvic Pain Syndrome An Effective Last Resort?Koo, Vincent S.W. MBBCh, MD, MRCSI; O'Brien, Aidan MBBCh, MD, FRCSI Author Information Department of Urology, Craigavon Area Hospital, Portadown, Northern Ireland, UK No funding received. Reprints: Vincent S.W. Koo, MBBCh, MD, MRCSI, Department of Urology, Craigavon Area Hospital, 68 Lurgan Road, Portadown, BT63 5QQ, Northern Ireland, UK (e-mail: [email protected]). Received June 19, 2010 Accepted August 7, 2010 The Clinical Journal of Pain 27(2):p 166-168, February 2011. | DOI: 10.1097/AJP.0b013e3181f89971 Buy Metrics Abstract Objective The chronic pelvic pain syndrome is a severely debilitating and protracted condition for patients and a challenging condition for clinicians to treat. We report our experience with an adjunctive treatment in four patients using peri- and intra-prostatic injection of Levobupivicaine and Methylprednisolone combination via a transperineal approach under general anaesthesia. Methods A retrospective observational report. Results All patients had found little or no relief of their perineal/pelvic pain with the use of antimicrobials, alpha blockers, anti-inflammatories, anticholinergics, Elmiron or with TURP. In all cases, the use of prostatic injection treatment has resulted in a complete eradication of perineal pain and significant improvement to quality of life for at least a period of time. Discussion We suggest prostatic injection treatment as a last resort therapy in relieving pain. Our report provides a basis for a larger randomised controlled study with longer term follow-up to evaluate its efficacy and durability. © 2011 Lippincott Williams & Wilkins, Inc.