Articles: PDF OnlyPsychological Aspects of Neuropathic PainHaythornthwaite, Jennifer A. Ph.D.; Benrud-Larson, Lisa M. Ph.D.Author Information Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland Address correspondence to Jennifer A. Haythornthwaite, Ph.D., Department of Psychiatry & Behavioral Sciences, 218 Meyer, 600 N. Wolfe St., Baltimore, MD 21287-7218; e-mail:[email protected] The Clinical Journal of Pain: June 2000 - Volume 16 - Issue 2 - p S101-S105 Buy Abstract Studies on the psychosocial impact of neuropathic pain conditions, including postherpetic neuralgia, diabetic neuropathy, complex regional pain syndrome, post spinal cord injury, postamputation, and AIDS-related neuropathy, are reviewed. Although limited, data are consistent with the larger literature on chronic pain and indicate that neuropathic pain reduces quality of life, including mood and physical and social functioning. Depression and pain coping strategies such as catastrophizing and social support predict pain severity, and a single diary study demonstrates a prospective relation between depressed mood and increased pain. Clinical trials of psychological interventions have not been reported, although some case series of successful treatment of neuropathic pain are reported, primarily in the area of biofeedback. Given the evidence indicating the broad impact of neuropathic pain on many areas of function, it is surprising that so few studies have investigated the impact of psychological interventions in these populations. © 2000 Lippincott Williams & Wilkins, Inc.