Article: PDF OnlyMiser Angela W.; Moore, Linda; Greene, Raymond; Gracely, Richard H.; Miser, James S.The Clinical Journal of Pain: 1986 - p 101-106 Buy Abstract Thirty continuous intravenous (i.v.) morphine infusions administered to 26 patients with cancer resulted in adequate pain control in 27 instances after inadequate control had been achieved with intermittent paren-teral narcotics. Three i.v. infusions were converted to subcutaneous infusions to avoid the use of an i.v. All infusions administered to control tumor-related pain provided adequate pain control; however, dose-limiting toxicity prevented adequate pain control during three (18%) infusions for non-tumor-related pain (mucositis) in spite of lower doses. Adverse reactions (11 episodes) appeared to be related to an interaction between the morphine and concurrent treatment in some cases. © Lippincott-Raven Publishers.