In the September 2023 issue Clinical Obstetrics and Gynecology there are two symposia topics:
Screening for and treating premalignant cervical disease has been one of the great success stories in gynecology, with significant reductions in death from cervical cancer. With improving understanding of the causes and development of this disease, the finer points of prevention and management have grown increasingly complex. Recommendations and guidelines have continued to evolve, and practicing clinicians may find it difficult to keep track of what’s new and recommended. In this issue, Dr. Richard Guido has enlisted a team of experts to explain the most recent strategies and the science behind them, both on cervical disease as well as closely related HPV-related anal disorders. This collection of articles covers all that clinicians need to know to provide thorough and up-to-date care to prevent and treat HPV-related disease.Noninvasive Screening for Prenatal Diagnosis:Fetal genetic conditions stand as a leading cause of high infant mortality globally. Hence, precise and prompt diagnosis, coupled with appropriate interventions, becomes pivotal. Until now, chorionic villus sampling (CVS) and amniocentesis have upheld their roles as the established gold standards in prenatal genetic diagnostics. However, risks associated with the procedure have led certain patients to exhibit hesitance in embracing these invasive techniques.
Contemporary Recommendations for Cervical Cancer and Anal Cancer Screening and Prevention:
In this edition, Dr. Maktabi et al. illuminate a crucial subject—the application of cell-free DNA (cfDNA), which directly embodies pure fetal genetic material—in noninvasive prenatal testing (NIPT). Their focus is to evaluate the diagnostic potential of cfDNA and to discuss its future prospects for clinical utilization. This comprehensive review encapsulates the entirety of what clinicians require to understand, disscuss the implicate and current information regarding cfDNA.
Co-Editors,Jonathan Schaffir, MD and Alireza Shamshirsaz, M.D.