Original ArticlePersistent Pelvic Pain in Patients With EndometriosisGreen, Isabel C. MD, MEHP; Burnett, Tatnai MD; Famuyide, Abimbola MBBS Author Information Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota The authors declare that they have nothing to disclose. Correspondence: Isabel C. Green, MD, MEHP, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN. E-mail:[email protected] Clinical Obstetrics and Gynecology: April 15, 2022 - Volume - Issue - 10.1097/GRF.0000000000000712 doi: 10.1097/GRF.0000000000000712 Buy PAP Metrics Abstract As our understanding of chronic pain conditions, including endometriosis-related pain and chronic pelvic pain evolves, the evaluation and management of patients should reflect our increasing appreciation of the role of central sensitization, comorbid conditions and biopsychosocial factors on the pain experience and treatment outcomes. This review provides a systematic approach to persistent pain in patients with endometriosis. Expanding the evaluation and treatment of endometriosis-related pain by all health care providers could limit unnecessary surgical interventions and best meet our patient’s needs. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.