What the Generalist Should Know About REIBone Health and Osteoporosis Prevention and TreatmentMUÑOZ, MARCUS BA*; ROBINSON, KATHLEEN MD, PhD†; SHIBLI-RAHHAL, AMAL MD, MS, MME†Author Information *University of Iowa Carver College of Medicine †Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa The authors declare that they have nothing to disclose. Correspondence: Amal Shibli-Rahhal, MD, MS, MME, Department of Internal Medicine, University of Iowa, 200 Hawkins Drive, Room 400 GH, Iowa City, IA. E-mail: [email protected] Clinical Obstetrics and Gynecology: December 2020 - Volume 63 - Issue 4 - p 770-787 doi: 10.1097/GRF.0000000000000572 Buy Metrics Abstract Postmenopausal osteoporosis is a common condition and is associated with increased risk of fracture, including hip and vertebral fractures that in turn can have devastating consequences on morbidity and mortality. In this article, we review the pathogenesis and diagnostic approach to postmenopausal osteoporosis. We review available nonpharmacologic and pharmacologic therapies and we discuss their clinical efficacy and complications, with a detailed discussion of atypical femur fractures and osteonecrosis of the jaw. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.