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Weaning From Long-term Opioid Therapy

MOSS, CHAILEE, MD; BOSSANO, CARLA, MD; PATEL, SILKA, MD; POWELL, ANNA, MD; CHAN SEAY, RACHEL, MD; BORAHAY, MOSTAFA A., MD, PhD

Clinical Obstetrics and Gynecology: March 2019 - Volume 62 - Issue 1 - p 98–109
doi: 10.1097/GRF.0000000000000425
Opioid Use, Misuse and Abuse: The Rise and Fall of a National Opioid Epidemic
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Opioid use for chronic noncancer pain poses a challenge to the gynecologist, and weaning opioids is often a goal for clinicians and patients. In some cases, opioid cessation can be achieved by weaning a patient’s prescribed opioid or with symptomatic management with long-acting opioids or alpha2-adrenergic medications. This review imparts a basic understanding of the physiology of opioid withdrawal, strategies for achieving opioid abstinence, medications for treating the symptoms of withdrawal, and alternatives to opioid taper.

Department of Gynecology and Obstetrics, Johns Hopkins University, Baltimore, Maryland

The authors declare that they have nothing to disclose.

Correspondence: Mostafa A. Borahay, MD, PhD, Department of Gynecology and Obstetrics, Johns Hopkins University, 4940 Eastern Ave., Baltimore, MD. E-mail: mboraha1@jhmi.edu

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