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Medical Management of Ectopic Pregnancy: A Comparison of Regimens


Clinical Obstetrics and Gynecology: June 2012 - Volume 55 - Issue 2 - p 440–447
doi: 10.1097/GRF.0b013e3182510a73
Ectopic Pregnancy

Medical management has become increasingly popular in the treatment of ectopic pregnancy. Given its convenience, for many it is used as a first-line treatment, however, this is not always the optimal choice for the patient. It is important to understand the options for medical treatment and when it is appropriate to treat a particular patient with medical management, or when one should opt for surgical management. This review outlines the different regimens for methotrexate administration and the associated risks and benefits to medical management.

*Penn Fertility Care

Department of Obstetrics and Gynecology, The Perelman School of Medicine, Penn Fertility Care, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

The authors declare that they have nothing to disclose.

K.B. was supported by the National Institutes of Health grants R01-HD036455 and K24HD060687.

Correspondence: Kurt Barnhart, MD, MSCE, Penn Fertility Care, Suite 800, Philadelphia, PA. E-mail:

© 2012 Lippincott Williams & Wilkins, Inc.