Ectopic PregnancyEctopic Pregnancy History, Incidence, Epidemiology, and Risk FactorsMARION, LAURA L. BS; MEEKS, GEORGE RODNEY MD Author Information Department of Obstetrics and Gynecology, University of Mississippi School of Medicine, Jackson, Mississippi The authors declare that they have nothing to disclose. Correspondence: George Rodney Meeks, MD, Department of Obstetrics and Gynecology, University of Mississippi School of Medicine, Jackson, MS 39216. E-mail: [email protected]; [email protected] Clinical Obstetrics and Gynecology 55(2):p 376-386, June 2012. | DOI: 10.1097/GRF.0b013e3182516d7b Buy Metrics Abstract Ectopic pregnancy is directly related to tubal infection, and so prevention of chlamydia and gonorrhea must be the watchword to lower its risk and incidence. With accurate determination of very low human chorionic gonadotropin concentrations and sonography, >85% of women are diagnosed before tubal rupture, which has led to medical therapy and laparoscopic surgery with tubal preservation and the potential for future fertility. Today, early intervention saves lives and reduces morbidity, but ectopic pregnancy still accounts for 4% to 10% of pregnancy-related deaths and leads to a high incidence of ectopic site gestations in subsequent pregnancies. © 2012 Lippincott Williams & Wilkins, Inc.