Cancer therapy can be lifesaving but significantly diminish female reproductive potential. This review provides an overview of the deleterious effects of cancer treatments on reproductive function, the fertility preservation options currently available for young women, and the outcomes of pregnancy after cancer treatment. In addition, special considerations for women who are diagnosed with cancer during pregnancy are discussed. To optimize the continuum of care for the patient, new corridors of communication between obstetricians, gynecologists, and oncology specialists must be developed to ensure the best outcomes for the patient, both in terms of cancer treatment and fertility preservation.
Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
The authors declare that they have nothing to disclose.
B.Y.K. and R.M.S. contributed equally to this work. Supported by the Oncofertility Consortium grant funded by the National Institutes of Health (NIH), grant number NIH RL1HD058295. The content is solely the responsibilities of the authors and does not necessarily reflect the official views of the NIH.
Correspondence: Teresa K. Woodruff, PhD, Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, 303 E. Superior Street 10-121, Chicago, IL 60611. E-mail: firstname.lastname@example.org.