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Fertility-Preserving Surgical Procedures for Patients With Gynecologic Malignancies


Clinical Obstetrics and Gynecology: December 2010 - Volume 53 - Issue 4 - p 804-814
doi: 10.1097/GRF.0b013e3181f97d02
Fertility Preservation: New Developments

Gynecologic malignancies often affect young women who are at the peak of their reproductive potential. The treatment for gynecologic malignancies often consists of removal of the ovaries or uterus, affecting the future fertility of these patients. Advances in surgical management have allowed patients to undergo more conservative treatment with preservation of their fertility. This review summarizes fertility-sparing surgical procedures for patients with gynecologic malignancies evaluating the role of radical trachelectomy and ovarian transposition in cervical cancer, hormonal therapy and hysteroscopic resection in endometrial cancer, and conservative surgery in ovarian cancer.

Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio

Correspondence: Peter G. Rose, MD, A-81, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH. E-mail:

© 2010 Lippincott Williams & Wilkins, Inc.