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Maternal Medical Disease and Stillbirth


Clinical Obstetrics and Gynecology: September 2010 - Volume 53 - Issue 3 - p 607-616
doi: 10.1097/GRF.0b013e3181eb2ca0

Stillbirth is one of the most common adverse pregnancy outcomes in the United States. Although there are certain maternal medical conditions that increase the risk of antepartum fetal death, advances in medical and obstetric care have decreased its incidence. The objective of this review was to examine the current stillbirth rates reported in pregnancies complicated by common medical diseases such as hypertension, diabetes, obesity, systemic lupus erythematosus, chronic renal disease, thyroid disorders, and cholestasis of pregnancy. Early diagnosis remains the key to provide increased surveillance and possible intervention to further decrease the likelihood of stillbirth.

Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York

Correspondence: Lynn L. Simpson, MD, Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032. E-mail:

© 2010 Lippincott Williams & Wilkins, Inc.