Respiratory Disease in PregnancyAcute Respiratory Failure in PregnancyMIGHTY, HUGH E. MDAuthor Information Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, School of Medicine, Baltimore, Maryland Correspondence: Hugh E. Mighty, MD, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, School of Medicine, 250 W. Pratt Street, Suite 880, Baltimore, MD. E-mail: email@example.com Clinical Obstetrics and Gynecology: June 2010 - Volume 53 - Issue 2 - p 360-368 doi: 10.1097/GRF.0b013e3181deb3f1 Buy SDC Metrics Abstract The maternal respiratory tract undergoes significant anatomic and physiologic changes during pregnancy, which increase maternal susceptibility to respiratory failure. Respiratory failure in pregnancy is relatively rare, but it remains one of the leading conditions requiring intensive care unit admission in pregnancy and carries a high risk of maternal and fetal morbidity and mortality. Acute respiratory failure can result from a variety of conditions, most of which are not pulmonary in origin. Early diagnosis of underlying disease is critical, as it will guide the management approach. Treatment goals during respiratory failure in the pregnant woman are similar to those outside of pregnancy—to maintain adequate ventilation and to provide hemodynamic and nutritional support. Additionally, the obstetrician will need to monitor fetal status and help to determine the best timing for delivery. © 2010 Lippincott Williams & Wilkins, Inc.