The Polycystic Ovary SyndromePolycystic Ovarian Syndrome: An Evidence-based Approach to Evaluation and Management of Diabetes and Cardiovascular Risks for Today's ClinicianLORENZ, LANDON B. MD; WILD, ROBERT A. MD, PhD, MPH Author Information Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma Correspondence: Robert A. Wild, MD, PhD, MPH, Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, 920 Stanton L. Young Blvd, WP 2410, Oklahoma City, Oklahoma 73104. E-mail: [email protected] Clinical Obstetrics and Gynecology: March 2007 - Volume 50 - Issue 1 - p 226-243 doi: 10.1097/GRF.0b013e31802f5197 Buy Metrics Abstract This review systematically addresses the evidence confirming polycystic ovary syndrome (PCOS) as a cardiovascular health threat. Literature in this area is void of long-term prospective studies to adequately evaluate outcome, but there is important evidence using surrogate markers for future development of and presence of cardiovascular disease and diabetes in women with PCOS. In addition, this article reviews the evidence regarding evaluation and management of cardiovascular risk factors in the population of women with PCOS. We seek to review the literature to determine when or if recommendations for management of women with PCOS should deviate from guidelines for the population at large. © 2007 Lippincott Williams & Wilkins, Inc.