Ictal–Interictal Continuum : Journal of Clinical Neurophysiology

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Invited Review

Ictal–Interictal Continuum

Kalamangalam, Giridhar P.*; Pohlmann-Eden, Bernhard

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Journal of Clinical Neurophysiology 35(4):p 274-278, July 2018. | DOI: 10.1097/WNP.0000000000000447

Abstract

Summary: 

The term “ictal–interictal” continuum has seen wide adoption in the critical care EEG domain, referring to the presence of abnormal periodic activity on the scalp EEG variably associated with seizures. The historical origin of the ictal–interictal continuum concept is discussed with a review of known and surmised physiological mechanisms for their origin and relationship to seizures. Therapeutic approaches to patients exhibiting ictal–interictal continuum EEG patterns are reviewed, and some open scientific questions highlighted. Further understanding of the ictal–interictal continuum is likely to significantly improve the care of the critically ill neurological patient.

Copyright © 2018 by the American Clinical Neurophysiology Society

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