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Generators of Short Latency Human Somatosensory-Evoked Potentials Recorded Over the Spine and Scalp

Lee, Eun-Kyu; Seyal, Masud

Section Editor(s): Nuwer, Marc R.

Journal of Clinical Neurophysiology: May 1998 - Volume 15 - Issue 3 - p 227-234
Original Contributions
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Somatosensory evoked potentials (SEPs) are most commonly obtained after stimulation of the median nerve and the posterior tibial nerve. SEPs reflect conduction of the afferent volley along the peripheral nerve, dorsal columns, and medial lemniscal pathways to the primary somatosensory cortex. Short-latency SEPs are recorded over the spine and scalp. After posterior tibial nerve stimulation, the following waveforms are recorded: N22, W3, the dorsal column volley, N29, P31, N34, and P37. After median nerve stimulation, the brachial plexus volley, dorsal column volley (N11), N13, P14, N18, N20, and P22 potentials are recorded. We discuss the current state of knowledge about the generators of these SEPs Such information is crucial for proper interpretation of SEP abnormalities.

Address correspondence and reprint requests to Dr. Eun-Kyu Lee, 2315 Stockton Blvd., Room 5308 Sacramento, CA 95817, U.S.A.

Department of Neurology, University of California, Davis Medical Center, Sacramento, California, U.S.A.

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