Case ReportsIncreased Frequency of Encopresis in a Child Diagnosed With Attention Deficit/Hyperactivity Disorder and Encopresis After Atomoxetine Use: A Case ReportYektaş, Çiğdem MD*; Cansiz, Mehmet Akif MD†; Tufan, Ali Evren MD†Author Information *Düzce University Medical Faculty, Child and Adolescent Psychiatry Department, Düzce, and †Izzet Baysal University Medical Faculty, Child and Adolescent Psycihatry Department, Bolu, Turkey. Address correspondence and reprint requests to Çiğdem Yektaş MD, Düzce University Medical Faculty, Child and Adolescent Psychiatry Department, Düzce, Turkey; E-mail: firstname.lastname@example.org Conflicts of Interest and Source of Funding: The authors have no conflicts of interest to declare. Clinical Neuropharmacology: 7/8 2016 - Volume 39 - Issue 4 - p 212-213 doi: 10.1097/WNF.0000000000000163 Buy Metrics Abstract Attention deficit hyperactivity disorder (ADHD) is among the most frequently reported coexisting psychiatric conditions in children with encopresis. Some case reports state that atomoxetine—a selective presynaptic norepinephrine reuptake inhibitor—approved for treatment of ADHD is also effective in the treatment of coexisting encopresis. Contrasting those reports, here we present a case diagnosed with ADHD and secondary encopresis without constipation whose encopretic symptoms increased after atomoxetine treatment and discuss possible mechanisms. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.