Case ReportsImpulse Control Disorder in a Patient on Long-Term Treatment With Bromocriptine for a MacroprolactinomaThondam, Sravan Kumar MBBS, MRCP*; Alusi, Sundus MBchB, MD, FRCP†; O'Driscoll, Kieran MBchB, BAO, FRCPsych†; Gilkes, Catherine E. MA Cantab, MBchB, FRCS (SN)‡; Cuthbertson, Daniel J. MBchB, MRCP, PhD*; Daousi, Christina MBchB, MD, FRCP*Author Information *Department of Endocrinology, University Hospital Aintree, Liverpool, England; and †Department of Neurology and Neuropsychiatry, and ‡Department of Neurosurgery, The Walton Centre for Neurology & Neurosurgery, Liverpool, England. Conflicts of Interest and Source of Funding: CD has received research grants from Merck Sharpe & Dohme (MSD), Otsuka, Eli Lilly, and the NovoNordisk UK Research Foundation. DJC has received research grants from Ipsen, Otsuka, and Pfizer but not in relation to the submitted work. SKT, SA, KO, and CEG have no conflicts of interest to declare. Address correspondence and reprint requests to Sravan Kumar Thondam, MBBS, MRCP, Department of Endocrinology, University of Liverpool, Clinical Sciences Centre, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, England; E-mail: firstname.lastname@example.org Clinical Neuropharmacology: September/October 2013 - Volume 36 - Issue 5 - p 170-172 doi: 10.1097/WNF.0b013e31829fc165 Buy Metrics Abstract Impulse control disorders (ICDs) constitute socially disruptive behaviors such as pathological gambling, impulsive eating, compulsive shopping, and hypersexuality. These conditions are well recognized in patients on dopamine agonist (DA) therapy for Parkinson disease. Dopamine agonists are widely used as first-line agents in the treatment of prolactinomas, but ICDs in this group of patients are relatively rare, perhaps because of lower therapeutic doses used. A review of the literature yielded only a few cases of ICDs in patients on DA treatment for prolactinomas. These symptoms are perhaps underreported because of lack of awareness among patients and health care professionals. Impulse control disorders are recognized psychiatric disorders that have significant psychological and social implications, and patients need to be counselled about this rare possibility when embarking on prolonged DA therapy. We describe a young patient with severe, socially disruptive impulsivity manifesting with pathological gambling who had been on long-term bromocriptine therapy for a macroprolactinoma. © 2013 by Lippincott Williams & Wilkins.