Review ArticleA Role for Pharmacotherapy in the Treatment of “Internet Addiction”Camardese, Giovanni MD; De Risio, Luisa MD; Di Nicola, Marco MD; Pizi, Giusy MD; Janiri, Luigi MDAuthor Information Institute of Psychiatry and Psychology, Catholic University of Sacred Heart, Rome, Italy. Conflicts of Interest and Source of Funding: The authors did not receive any financial support for the conduct of the research. The authors have no conflicts of interest to declare. All authors contributed in a significant way to the manuscript and agreed on this final version of the manuscript. Address correspondence and reprint requests to Giovanni Camardese, MD, Viale delle Medaglie d’Oro, 163-00136 Rome, Italy; E-mail: email@example.com Clinical Neuropharmacology: November/December 2012 - Volume 35 - Issue 6 - p 283-289 doi: 10.1097/WNF.0b013e31827172e5 Buy Metrics Abstract The advent of the Internet is among the most significant changes in recent decades and has greatly affected the entire range of human experience. However, it has, in turn, led to the emergence of psychopathological features of addiction linked to its use. Literature on the clinical management of the distress related to Internet use systematically measures up to an evolving nosography, with ambiguous definitions of the phenomenon and a diversity of diagnostic, prognostic, and therapeutic criteria. To date, case studies on “Internet addiction” treatment are rather limited, and no standard clinical treatment protocols exist. With regard to pharmacological treatment options, empirical or anecdotal assessments are mostly referred to. The aim of this article was to review current literature on Internet addiction treatment and assess the extent to which specific pharmacological interventions alleviate these patients’ symptomatic burden, to propose a rationale that may guide the therapeutic approach. To this end, we also explored pharmacological interventions that target patterns of comorbidity and underlying psychopathological dimensions shared with other behavioral or substance addictions. © 2012 Lippincott Williams & Wilkins, Inc.