Case ReportsRestless Legs Syndrome Responsive to Rasagiline Treatment: A Case ReportBabacan-Yildiz, Gulsen MD; Gursoy, Esra MD; Kolukisa, Mehmet MD; Celebi, Arif MDAuthor Information Department of Neurology, Faculty of Medicine, Bezmi Alem Vakif University, Istanbul, Turkey. Conflicts of Interest and Source of Funding: The authors have no conflicts of interest to declare. Address correspondence and reprint requests to: Gulsen Babacan-Yildiz, MD, Department of Neurology, Faculty of Medicine, Bezmialem Vakif University, Vatan Cad. 34093 Fatih, Istanbul, Turkey; E-mail: email@example.com Clinical Neuropharmacology: March/April 2012 - Volume 35 - Issue 2 - p 88-89 doi: 10.1097/WNF.0b013e31824c1c3f Buy Metrics Abstract We describe a patient with idiopathic restless legs syndrome (iRLS) who was responsive to rasagiline treatment. A 70-year-old woman presented with an 8-year history of iRLS symptoms and a 1-year history of resting tremor. The patient met the UK Parkinson’s Disease Society Brain Bank Clinical Diagnostic Criteria (UK Parkinson Disease [PD] Brain Bank criteria) for the diagnosis of idiopathic PD and the criteria of the International Restless Legs Syndrome Study Group for the diagnosis of iRLS. One milligram of rasagiline once daily was started with the diagnosis of early PD as monotherapy. At week 8, the patient was almost iRLS symptoms free. Rasagiline has also been shown to mildly improve PD symptoms. Rasagiline was well tolerated during the follow-up. We suggest that rasagiline could represent a useful therapeutic option in the treatment of iRLS. © 2012 Lippincott Williams & Wilkins, Inc.