Case ReportLevetiracetam-Responding Paroxysmal Nonkinesigenic DyskinesiaAlemdar, Murat MD; Iseri, Pervin MD; Selekler, Macit MD; Komsuoğlu, Sezer Şener MD Author Information From the Department of Neurology, Faculty of Medicine, University of Kocaeli, Kocaeli, Turkey. Address correspondence and reprint requests to Murat Alemdar, MD, Kocaeli Universitesi, Tip Fakultesi, Noroloji A.D., 41380, Umuttepe, Izmit, Kocaeli, Turkey; E-mail: [email protected] Clinical Neuropharmacology: July 2007 - Volume 30 - Issue 4 - p 241-244 doi: 10.1097/wnf.0b013e31803b9415 Buy Metrics Abstract We report on a patient with 7-year history of short-lasting paroxysmal nonkinesigenic dyskinesia. The episodes occurred 100 to 125 times per day, lasted from 5 seconds to 3 minutes, and were not suppressed with sleeping, underlining the heterogeneity of phenomenology in paroxysmal dyskinesias. Neuroimaging studies showed calcifications in the basal ganglia, thalamus, brain stem, and subcortical and cerebellar regions. He was diagnosed with idiopathic hypoparathyroidism. After failure of valproate, he responded well to levetiracetam (1000 mg/d). This report revealed that intracerebral calcifications secondary to hypoparathyroidism could present as paroxysmal nonkinesigenic dyskinesia, and levetiracetam could be effective in this particular entity. © 2007 Lippincott Williams & Wilkins, Inc.