Case ReportsTreatment of Primary Progressive Freezing of Gait With High Doses of SelegilineZúñiga, Carlos MD; Lester, Jacobo MD; Cersósimo, María Graciela MD; Díaz, Sergio MD; Micheli, Federico E. MD, PhD Author Information Parkinson's Disease and Movement Disorders Unit, Hospital de Clínicas "José de San Martín,“ Buenos Aires, Argentina. Reprints: Federico E. Micheli MD, PhD Juncal 1695- P 5 Dpto J (1062), Buenos Aires, Argentina (e-mail: [email protected]). Clinical Neuropharmacology: January 2006 - Volume 29 - Issue 1 - p 20-21 Buy Abstract We report the case of a 76-year-old, right-handed woman with progressive primary freezing of gait. Despite several therapeutic strategies, she continued to worsen to the point that she became confined to a wheelchair. Treatment with selegiline in doses up to 20 mg/d led to marked improvement of the gait disorder. This case illustrates that selegiline can be an option for patients with freezing of gait other than those with Parkinson's disease. © 2006 Lippincott Williams & Wilkins, Inc.