Brief ReportsPramipexole Ameliorates Neurologic and Psychiatric Symptoms in a Westphal Variant of Huntington's DiseaseBonelli, Raphael M.*; Niederwieser, Gerald*; Diez, Josef*; Gruber, Andreas†; Költringer, Peter*Author Information *Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Graz, Austria; and †Department of Neurosurgery, University of Vienna, Vienna, Austria Address correspondence and reprint requests to R.M. Bonelli, Department of Neuorology and Psychiatry, Hospital BHB Eggenberg, Bergstraβe 27, 8020 Graz, Austria; E-mail: email@example.com. Clinical Neuropharmacology: January-February 2002 - Volume 25 - Issue 1 - p 58-60 Buy Abstract Levodopa is recommended as a therapeutic approach for patients with the hypokinetic-rigid, Westphal variant of Huntington's disease, but no guidelines are available for the case of nonrespondence to levodopa. In this study, however, we report a 34-year-old woman with this rare variant who showed a clear-cut improvement in motor function and depressive symptoms after treatment with pramipexole, a new dopamine agonist. © 2002 Lippincott Williams & Wilkins, Inc.