Review ArticleKlippel-Feil syndrome: a review of the literatureFrikha, RimAuthor Information Faculty of Medicine of Sfax, University of Sfax, Tunisia Received 29 June 2017 Accepted 20 August 2019 Correspondence to Rim Frikha, MD, Faculty of Medicine of Sfax, University of Sfax, Tunisia, Tel: +216 74 241 888; fax: +216 74 246 217; e-mail: [email protected], ORCID ID: 0000-0003-4415-8785 Clinical Dysmorphology: January 2020 - Volume 29 - Issue 1 - p 35-37 doi: 10.1097/MCD.0000000000000301 Buy Metrics Abstract Klippel-Feil syndrome is a congenital defect in the formation or segmentation of the cervical spine. A wide spectrum of associated anomalies may be present. This heterogeneity has complicated clarification of the genetic causes and management of patient’s with congenital vertebral fusion. In this review, we focussed on clinical heterogeneity; radiographic abnormalities and genetic etiology in Klippel-Feil syndrome. We insist on comprehensive evaluation and delineation of diagnostic and prognostic classes. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.