ORIGINAL ARTICLESFilippi syndrome: two cases with ectodermal features, expanding the phenotypeSharif, S.; Donnai, D.Author Information Academic Unit of Medical Genetics and Regional Genetic Service, St Mary's Hospital, Manchester M13 0JH, UK Correspondence and requests for reprints to S. Sharif, Academic Unit of Medical Genetics and Regional Genetic Service, St Mary's Hospital, Manchester, M13 0JH, UK Tel: +44 161 276 6269; fax: +44 161 276 6145; e-mail: email@example.com Received 18 June 2004 Accepted 15 July 2004 Clinical Dysmorphology: October 2004 - Volume 13 - Issue 4 - p 221-226 Buy Abstract We report two unrelated children with Filippi syndrome. Both show typical facial dysmorphism, syndactyly of fingers and toes, growth retardation, postnatal microcephaly and developmental delay, particularly involving speech. In addition both children have unusual teeth and hair. We review the literature and propose that neurological and ectodermal involvement may be under-recognised features of the syndrome. © 2004 Lippincott Williams & Wilkins, Inc.