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Changes in Peripheral Refraction, Higher-Order Aberrations, and Accommodative Lag With a Radial Refractive Gradient Contact Lens in Young Myopes

Pauné, Jaume M.Sc.; Thivent, Solène M.Sc.; Armengol, Jesús Ph.D.; Quevedo, Lluisa Ph.D.; Faria-Ribeiro, Miguel M.Sc.; González-Méijome, José M. Ph.D.

Eye & Contact Lens: Science & Clinical Practice: November 2016 - Volume 42 - Issue 6 - p 380–387
doi: 10.1097/ICL.0000000000000222

Purpose: To evaluate changes in the peripheral refraction (PR), visual quality, and accommodative lag with a novel soft radial refractive gradient (SRRG) experimental contact lens that produces peripheral myopic defocus.

Methods: 59 myopic right eyes were fitted with the lens. The PR was measured up to 30° in the nasal and temporal horizontal visual fields and compared with values obtained without the lens. The accommodative lag was measured monocularly using the distance-induced condition method at 40 cm, and the higher-order aberrations (HOAs) of the entire eye were obtained for 3- and 5-mm pupils by aberrometry. Visual performance was assessed through contrast sensitivity function (CSF).

Results: With the lens, the relative PR became significantly less hyperopic from 30° to 15° temporally and 30° nasally in the M and J0 refractive components (P<0.05). Cylinder foci showed significant myopization from 30° to 15° temporally and 30° to 25° nasally (P<0.05). The HOAs increased significantly, the CSF decreased slightly but reached statistical significance for 6 and 12 cycles per degree (P<0.05), and the accommodative lag decreased significantly with the SRRG lens (P=0.0001). There was a moderate correlation between HOAs and CSF at medium and high spatial frequencies.

Conclusion: The SRRG lens induced a significant change in PR, particularly in the temporal retina. Tangential and sagittal foci changed significantly in the peripheral nasal and temporal retina. The decreased accommodative lag and increased HOAs particularly in coma-like aberration may positively affect myopia control. A longitudinal study is needed to confirm this potential.

Department of Optometry (J.P.), Centro Médico Teknon, Barcelona, Spain; Department of Optics and Optometry (S.T., J.A., L.Q.), Polytechnic University of Catalonia—Barcelona Tech, Spain; and Clinical & Experimental Optometry Research Lab (CEORLab) (J.M.G.-M., M.F.-R.), Department and Center of Physics, University of Minho, Braga, Portugal.

Address correspondence to José M. González-Méijome, Ph.D., Clinical & Experimental Optometry Research Lab, Department of Physics (Optometry), University of Minho, 4710-057 Braga, Portugal; e-mail:

J. Pauné has proprietary and financial interests in the manufacturing and distribution of lenses evaluated in this study and holds the Spanish Patent Application P-2406381 for the lenses. The remaining authors have no funding or conflicts of interest to disclose.

Supported in part by Fundação para Ciência e Tecnologia, Lisbon, Portugal (Projects: PTDC/SAU-BEB/098392/2008 and PTDC/SAU-BEB/098391/2008).

Accepted October 19, 2015

© 2016 Contact Lens Association of Ophthalmologists, Inc.