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Accounting for Ethnicity-Related Differences in Ocular Surface Integrity as a Step Toward Understanding Contact Lens Discomfort

Chan, Stefanie M. O.D.; Svitova, Tatyana F. Ph.D.; Lin, Meng C. O.D., Ph.D.

Eye & Contact Lens: Science & Clinical Practice: January 2017 - Volume 43 - Issue 1 - p 23–31
doi: 10.1097/ICL.0000000000000342
Review Article

Abstract: Contact lens discomfort is a common problem that can lead to unsuccessful or limited contact lens wear. Although many factors may contribute to contact lens discomfort, limited research has explored the influence of ethnicity-related differences in the anatomy and physiology of the ocular surface. Therefore, we performed a search of the literature in PubMed using key words related to “ocular surface” paired with the terms “race” and “ethnicity.” The goal of this review was to determine potential areas of research regarding ethnicity differences, particularly between Asian and non-Asian eyes, in ocular surface integrity to advance our understanding of contact lens discomfort.

Clinical Research Center (S.M.C., T.F.S., M.C.L.), School of Optometry, University of California, Berkeley, CA; and Vision Science Program (M.C.L.), University of California, Berkeley, CA.

Address correspondence to Meng C. Lin, O.D., Ph.D., School of Optometry, University of California, 360 Minor Hall, Berkeley, CA 94720-2020; e-mail:

S. M. Chan has been financially supported by Michael G. Harris Cornea and Contact Lens Residency. The remaining authors have no funding or conflicts of interest to disclose.

Accepted August 22, 2016

© 2017 Contact Lens Association of Ophthalmologists, Inc.