Various materials have been placed in the corneal stroma to modify a spherical refractive error (usually hyperopic). As the surgical procedures evolved to simplify the insertion process so has the quality and biocompatibility of the implanted materials. Failures have been due to excessive inlay dimensions, bioincompatibility of the materials used, poor choice of test model, or combinations of the above. We present a thorough analysis of the history of the intracorneal inlay and the materials and techniques used up to and including the current materials and techniques available for the correction of spherical refractive errors.
Gavin Herbert Eye Institute (P.S.B.), University of California Irvine, Irvine, CA; and AcuFocus, Inc. (P.S.B., L.L., C.v.d.P.), Irvine, CA.
Address correspondence to Perry S. Binder, M.S., M.D., 2500 6th Avenue, Unit 307, San Diego, CA 92103; e-mail: firstname.lastname@example.org
L. Lin and C. van de Pol are employees for AcuFocus, Inc., and P. S. Binder is a consultant for AcuFocus, Inc. The authors have no other conflicts of interest to disclose.
Supported by AcuFocus, Inc.
Accepted December 01, 2014