Review ArticleWettability and Silicone Hydrogel Lenses A ReviewKeir, Nancy O.D., Ph.D.; Jones, Lyndon Ph.D. Author Information Centre for Contact Lens Research (N.K., L.J.), School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada. Address correspondence and reprint requests to Nancy Keir, O.D., Ph.D., Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada; e-mail: [email protected] The authors have no financial or conflict of interest in the material presented in this article; however, both authors received an honorarium from CLAO for presenting the paper at the SiHy symposium (Silicone Hydrogel Lenses - Ten Years Later) and preparation of the manuscript for this special issue of Eye & Contact Lens. Accepted November 8, 2012 Eye & Contact Lens: Science & Clinical Practice: January 2013 - Volume 39 - Issue 1 - p 100-108 doi: 10.1097/ICL.0b013e31827d546e Buy Metrics Abstract One of the major breakthroughs in the development of silicone hydrogel contact lenses has related to the ability of manufacturers to overcome the surface hydrophobicity that occurred with silicone elastomer lenses. However, the wettability of silicone hydrogel lenses continues to be of interest as a potential link between in vivo lens performance and contact lens–related comfort. This article will review some of the knowledge we have gained in the area of contact lens wettability over the past decade and will discuss some of the challenges related to its measurement. © 2013 Lippincott Williams & Wilkins, Inc.