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Effect of Multizone Refractive Multifocal Contact Lenses on Standard Automated Perimetry

Madrid-Costa, David Ph.D.; Ruiz-Alcocer, Javier O.D., M.Sc.; García-Lázaro, Santiago Ph.D.; Albarrán-Diego, César O.D., M.Sc.; Ferrer-Blasco, Teresa Ph.D.

doi: 10.1097/ICL.0b013e31825fed3b

Purpose: The aim of this study was to evaluate whether the creation of 2 foci (distance and near) provided by multizone refractive multifocal contact lenses (CLs) for presbyopia correction affects the measurements on Humphreys 24-2 Swedish interactive threshold algorithm (SITA) standard automated perimetry (SAP).

Methods: In this crossover study, 30 subjects were fitted in random order with either a multifocal CL or a monofocal CL. After 1 month, a Humphrey 24-2 SITA standard strategy was performed. The visual field global indices (the mean deviation [MD] and pattern standard deviation [PSD]), reliability indices, test duration, and number of depressed points deviating at P<5%, P<2%, P<1%, and P<0.5% on pattern deviation probability plots were determined and compared between multifocal and monofocal CLs.

Results: Thirty eyes of 30 subjects were included in this study. There were no statistically significant differences in reliability indices or test duration. There was a statistically significant reduction in the MD with the multifocal CL compared with monfocal CL (P=0.001). Differences were not found in PSD nor in the number of depressed points deviating at P<5%, P<2%, P<1%, and P<0.5% in the pattern deviation probability maps studied.

Conclusions: The results of this study suggest that the multizone refractive lens produces a generalized depression in threshold sensitivity as measured by the Humphreys 24-2 SITA SAP.

Optometry Research Group (D.M.-C., J.R.-A., S.G.-L., C.A.-D., T.F.-B.), Optics Department, University of Valencia, Valencia, Spain.

Address correspondence and reprint requests to David Madrid-Costa, Ph.D., Optometry Research Group, Optics Department, University of Valencia, Spain; e-mail:

Supported in part by a Ministerio de Ciencia e Innovación Research Grants (#SAF2008-01114# and #SAF2009-13342#) and a scholarship Jose Castillejo to Robert Montés-Micó.

The authors have no proprietary interest in any of the materials mentioned in this article.

Accepted May 16, 2012

© 2012 Contact Lens Association of Ophthalmologists, Inc.