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Development of Methicillin-Resistant Staphylococcus aureus Keratitis in a Dry Eye Patient With a Therapeutic Contact Lens

Koh, Shizuka M.D.; Maeda, Naoyuki M.D.; Soma, Takeshi M.D.; Hori, Yuichi M.D.; Tsujikawa, Motokazu M.D.; Watanabe, Hitoshi M.D.; Nishida, Kohji M.D.

doi: 10.1097/ICL.0b013e31823ff1f4
Case Report

Purpose: The aim was to report a case of methicillin-resistant Staphylococcus aureus (MRSA) keratitis possibly associated with the use of a silicone hydrogel soft contact lens in a patient with dry eye.

Methods: This is a case report.

Results: A 61-year-old woman who wore a silicone hydrogel lens as therapy for filamentary keratitis with severe dry eye presented with pain and redness in her left eye. She developed severe keratitis with ulceration and hypopyon. The MRSA grew in the culture, and intensive systemic and topical antibiotics resolved the corneal keratitis.

Conclusions: The MRSA may cause infectious keratitis associated with silicone hydrogel contact lens therapy.

Department of Ophthalmology (S.K, N.M, T.S, M.T, H.W., K.N.), Osaka University Graduate School of Medicine, Suita, Japan; and Department of Ophthalmology (Y.H.), Toho University Sakura Medical School, Chiba, Japan.

The authors have no funding or conflicts of interest to disclose.

Address correspondence and reprint requests to Shizuka Koh, M.D., Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita 565-0871, Japan; e-mail:

Accepted November 1, 2011

© 2012 Lippincott Williams & Wilkins, Inc.