Case ReportBubble and Corneal Dimple Formation After the First Overnight Wear of an Orthokeratology Lens: A Case SeriesStillitano, Iane M.D; Maidana, Eduardo M.D; Lui, Marcelo M.D; Lipener, César M.D; Höfling-Lima, Ana Luisa M.DAuthor Information From the Contact Lens Sector, Department of Ophthalmology, Vision Institute of Federal University of Sao Paulo, Paulista School of Medicine (UNIFESP/EPM), Sao Paulo, Brazil. None of the authors has a financial or proprietary interest in any aspect of this article. Address correspondence and reprint requests to Dr. I. Stillitano, Rua Botucatu 822, Sao Paulo-SP, Brazil 04023-062; e-mail: [email protected] Accepted September 29, 2006. Eye & Contact Lens: Science & Clinical Practice: September 2007 - Volume 33 - Issue 5 - p 253-258 doi: 10.1097/01.icl.0000252870.05807.ea Buy Metrics Abstract Purpose. To report the first documented case series of bubbles and corneal dimples associated with corneal reshaping after the first overnight wear of an orthokeratology lens. Methods. Three cases of transient corneal dimples are described after the first overnight use of the Be Free orthokeratology lens (BE; Ultravision Pty. Ltd., Brisbane, Australia) related to bubble formation under the posterior lens surface. Results. The corneal dimples were located most centrally and peripherally in correspondence to the reverse curve and did not produce a significant change in best-corrected visual acuity except in one patient, who had many bubbles in the central cornea. Conclusions. The current findings suggest that the precorneal tear film between the corneal surface and the posterior orthokeratology contact lens surface plays a role in the development of bubbles and corneal dimples. © 2007 Lippincott Williams & Wilkins, Inc.