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Corneal Ulcers in Two Children Wearing Paragon Corneal Refractive Therapy Lenses

Macsai, Marian S. M.D.

Eye & Contact Lens: Science & Clinical Practice: January 2005 - Volume 31 - Issue 1 - p 9-11
doi: 10.1097/01.ICL.0000151947.99251.6D

Objectives. To report the development of corneal ulcers in two children wearing Paragon Corneal Refractive Therapy (CRT) lenses.

Methods. Two case reports of children who developed corneal ulcers when fit with Paragon CRT contact lenses, which were worn nightly, are discussed. Each patient presented with a bacterial corneal ulcer after wearing CRT contact lenses for less than 6 months. In the first patient, Pseudomonas aeruginosa was identified as the causative organism. In the second patient, Haemophilus influenza was cultured from the ulcer.

Results. Both patients were treated with intensive, fortified antibiotics with rapid resolution of the corneal ulcers and preservation of vision. No surgical intervention was required.

Conclusions. Paragon CRT lenses have been approved for use in patients of all ages. When used in children, these lenses may present unique problems. The absolute incidence of bacterial corneal ulcers in patients with CRT lenses are unknown. Severe caution should be used before prescribing CRT lenses for children and informed consent should include potential sight-threatening corneal ulcers.

Division of Ophthalmology, Evanston Northwestern Healthcare, and Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Supported in part by an unrestricted departmental grant from the Research to Prevent Blindness Inc., New York, New York.

Address correspondence and reprint requests to Dr. Marian S. Macsai, Chief, Division of Ophthalmology, Evanston Northwestern Healthcare, 2050 Pfingsten Road., Suite 220, Glenview, IL 60026; e-mail:

Accepted November 10, 2004.

© 2005 Lippincott Williams & Wilkins, Inc.