CONTENTS: SESSION V: RIGID LENSES, SOFT LENSES, OR LASIK: WHICH WOULD YOU CHOOSE?Microbial Keratitis and Vision Loss with Contact LensesHolden, Brien A. D.Sc., F.A.A.O.; Sweeney, Deborah F. Ph.D., F.A.A.O.; Sankaridurg, Padmaja R. Ph.D.; Carnt, Nicole B.Optom.; Edwards, Katie B.Optom.; Stretton, Serina Ph.D.; Stapleton, Fiona Ph.D., F.A.A.O.Author Information From the Cornea and Contact Lens Research Unit, School of Optometry and Vision Science, and the Cooperative Research Centre for Eye Research and Technology, The University of New South Wales, Sydney, Australia. Accepted August 15, 2002. Address correspondence to : B.A. Holden, The Cooperative Research Centre for Eye Research and Technology (CRCERT), The University of New South Wales, Sydney NSW 2052, Australia. Phone: 61-2-9385 7418; fax: 61-2-9385 7401; e-mail: [email protected] CRCERT was involved in the development of the high-Dk soft lens material lotrafilcon A and have a royalty agreement with CIBA Vision. Eye & Contact Lens: Science & Clinical Practice: January 2003 - Volume 29 - Issue 1 - p S131-S134 Buy Abstract Purpose. Microbial keratitis is the only sight-threatening adverse event that occurs with contact lens wear. This article gives a preliminary estimation of the incidence of microbial keratitis and vision loss with continuous-wear contact lenses made from highly oxygen permeable (Dk) materials. Methods. The most up-to-date data available on microbial keratitis and vision loss are collected from a range of sources including industry, private practice, and publications and is reviewed. Results. There have been 16 cases of microbial keratitis with high-Dk silicone hydrogel lenses. Of the 13 where data are available, none have lost two or more lines of best-corrected visual acuity (BCVA). Conclusion. First approximation indicates that the incidence of microbial keratitis with high-Dk silicone hydrogel lenses may be lower than the incidence with low-Dk soft lenses during extended wear. The rate of loss of more than two lines of BCVA is low in patients that develop microbial keratitis with low- and high-Dk soft lenses. © 2003 Lippincott Williams & Wilkins, Inc.