Complications related to contact lens-induced anoxia in the keratoconic eye are well documented, but the underlying mechanisms are poorly understood. This study compared topographical changes in corneal thickness and anterior corneal radius following SoftPerm (Ciba Vision, Atlanta, GA) (rigid-and-soft combination) lens wear in a group of keratoconic and normal individuals.
Video keratoscopic (VKS) (EyeSys, Houston, TX) and ultrasonographic pachometry
measurements were taken at nine ocular locations, at central, mid-peripheral, and peripheral corneal areas of keratoconic and normal subjects. Subjects were subsequently fitted with SoftPerm lenses and further measurements of corneal topography
and thickness were noted after 1 day, 2 weeks, and 1 month of daily wear.
Corneal thickness increased significantly in normal and keratoconic eyes following SoftPerm lens
wear. Radius values obtained from the VKS measurements indicated that a significant and progressive degree of corneal flattening occurred for the keratoconic subjects at the 1-day, 2-week, and 1-month intervals, in contrast to the normal group, whose corneal radii remained unchanged.
Conclusions. Corneal swelling
occurs in both normal and keratoconic corneas following SoftPerm lens
wear. Differences in the apparent central edema response within the keratoconic group may relate to the ease with which these corneas may be molded by a rigid contact lens.