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Botulinum Toxin for Chronic Exertional Compartment Syndrome: A Case Report With 14 Month Follow-Up

Baria, Michael R. MD; Sellon, Jacob L. MD

Clinical Journal of Sport Medicine: November 2016 - Volume 26 - Issue 6 - p e111–e113
doi: 10.1097/JSM.0000000000000289
Case Report
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Abstract: Chronic exertional compartment syndrome (CECS) presents a unique therapeutic challenge. Fasciotomy, currently the most well accepted treatment approach, still has a significant number of treatment failures, demonstrating the need for additional options. Botulinum toxin has been introduced as a potential therapeutic agent, but long-term outcomes are unknown. We present the longest documented follow-up (14 months) of a CECS case treated with botulinum toxin injections. At 14 months follow-up, the patient reported continued pain relief and had resumed her active lifestyle without any adverse effects. Although more research is needed to optimize patient selection and treatment protocol, this case illustrates the potential for botulinum toxin as a long duration, low risk alternative treatment option for CECS.

Department of Physical Medicine & Rehabilitation, Sports Medicine Center, Mayo Clinic, Rochester, Minnesota.

Corresponding Author: Jacob L. Sellon, MD, Department of Physical Medicine & Rehabilitation, Sports Medicine Center, Mayo Clinic, W14 Mayo Building, 200 1st St, SW, Rochester, MN 55905 (sellon.jacob@mayo.edu).

Presented as an abstract at the American Medical Society for Sports Medicine Annual Meeting, April 8, 2014.

The authors report no conflicts of interest.

Received February 03, 2015

Accepted October 19, 2015

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