Feature ArticleInterdisciplinary Collaboration Among Nursing and Computer Science to Refine a Pharmacogenetics Clinical Decision Support Tool Via Mobile ApplicationDodson, Crystal PhD, RN, CNE; Layman, Lucas PhD Author Information Author Affiliation: University of North Carolina Wilmington. This study was funded by the Oncology Nursing Foundation (#581660). The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Corresponding author: Crystal Dodson, PhD, RN, CNE, University of North Carolina Wilmington, 601 S College Rd, Wilmington, NC 28403 ([email protected]). CIN: Computers, Informatics, Nursing: October 14, 2022 - Volume - Issue - 10.1097/CIN.0000000000000960 doi: 10.1097/CIN.0000000000000960 Buy PAP Metrics Abstract In previous work, a prototype clinical decision support mobile application was created that accepts a patient's genomic profile information and provides information and rationale for the prescription of certain oncology medications. The response to the instrument was overwhelmingly positive by healthcare providers in the oncology field who tested the instrument. This article reports on the interdisciplinary collaboration among nursing and computer science to redesign and reimplement a new version of the instrument with expanded functionality and improved usability. This article describes the functionality, usability considerations, and usability evaluation of the instrument over three versions. The current version is Web-based and responsive to different screen sizes (desktop, tablet, mobile), features improved usability, and expands the number of gene-drug recommendations provided based on Clinical Pharmacogenetics Implementation Consortium dosing guidelines. This project represents a successful new collaboration between the nursing and computer science disciplines. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.