FEATURE ARTICLEClinical Decision Support Systems in Nursing: Synthesis of the Science for Evidence-Based PracticeANDERSON, JANE A. MSN, RN, FNP, BC; WILLSON, PAMELA PhD, RN, FNP, BCAuthor Information Author Affiliations: Stroke Center, Michael E. DeBakey Veterans Affairs Medical Center (Ms Anderson), and College of Nursing, Prairie View A&M University (Dr Willson), Houston, TX. Corresponding author: Jane A. Anderson, MSN, RN, FNP, BC, Stroke Center, Michael E. DeBakey Veterans Affairs Medical Center, 2002 Holcombe Blvd., Houston, TX 77030 (firstname.lastname@example.org). CIN: Computers, Informatics, Nursing: May-June 2008 - Volume 26 - Issue 3 - p 151-158 doi: 10.1097/01.NCN.0000304783.72811.8e Buy Metrics Abstract The aim of this article is to present a synthesis of the research literature on the state of nursing science regarding the development, use, and application of clinical decision support systems for the implementation of evidence-based practice in nursing. The authors sought to answer three specific questions in this metasynthesis: (1) What progress has nursing science made regarding the development and use of clinical decision support systems?; (2) What research methods and theoretical models are being applied by nurse researchers in this area?; and (3)Are there evidence-adaptive clinical decision support systems designed specifically to aid nurses' decisions related to evidence-based practice? Of 183 articles, 17 were included in the final analysis, and six were specific for clinical decision support systems to aid nurses in evidence-based practice. Implications for practice are considered, and recommendations for future research are made. © 2008 Lippincott Williams & Wilkins, Inc.