CONTINUING EDUCATIONComputerized Information Management for Institutional Review BoardsHOOD, MAUREEN N. MS, RN; GUGERTY, BRIAN DNS, RN; LEVINE, RICHARD PhD; HO, VINCENT B. MDAuthor Information Department of Radiology and Radiological Sciences(Ms Hood and Dr Ho), and Office of Research (Dr Levine), and Uniformed Services University of the Health Sciences, Bethesda, MD and the University of Maryland, School of Nursing, Baltimore, MD (Ms Hood and Dr Gugerty). Corresponding author: Maureen N. Hood, MS, RN, Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814 (e-mail: email@example.com). The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or reflecting the views of the Uniformed Services University of the Health Sciences or the Department of Defense. CIN: Computers, Informatics, Nursing: July-August 2005 - Volume 23 - Issue 4 - p 190-198 Buy Take the CE Test Abstract The use of human subjects for medical research in most industrialized nations requires the scientific and ethical scrutiny of research proposals by a governing institutional review board (IRB) or its equivalent. As part of their primary charge to protect human subjects, IRBs are responsible for the regulatory oversight of not only the research protocol itself but also the research conduct of the investigators and, if applicable, the funding sponsor. This article will discuss the regulatory requirements for an accurate account of IRB protocols and investigators and present an overview of the general flow of information for an IRB protocol. The current and potential uses of information management systems by IRBs will also be reviewed and accompanied by a discussion of the potential advantages and disadvantages of various computerized information systems for management of clinical research. © 2005 Lippincott Williams & Wilkins, Inc.