Original ArticlesBlood Pressure Management Following Acute Ischemic Stroke A Review of Primary LiteratureTucker, Natalie PharmD; Stoffel, Jaclyn M. PharmD, BCPS; Hayes, Lisa PharmD, BCCCP; Jones, G. Morgan PharmD, BCCCP, FCCMAuthor Information Methodist University Hospital, Memphis, Tennessee (Drs Tucker, Stoffel, Hayes, and Jones); and College of Pharmacy (Drs Stoffel, Hayes, and Jones) and Medicine (Jones), University of Tennessee Health Sciences Center, Memphis. Correspondence: G. Morgan Jones, PharmD, BCCCP, FCCM, Pharmacy Department, Methodist University Hospital, 1265 Union Ave, Memphis, TN 38104 (firstname.lastname@example.org). The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Critical Care Nursing Quarterly: April/June 2020 - Volume 43 - Issue 2 - p 109-121 doi: 10.1097/CNQ.0000000000000297 Buy Metrics Abstract Elevated blood pressure is common in patients with acute ischemic stroke. While this may occur secondary to the body's own response to preserve cerebral blood flow, elevated blood pressure may also increase the risk of hemorrhagic transformation. Current guidelines recommend various blood pressure goals based upon multiple factors, including thresholds specific to certain treatment interventions. Despite these guidelines, there is limited evidence to support specific blood pressure targets, and variability in clinical practice is common. The purpose of this review was to discuss blood pressure management in adult patients with acute ischemic stroke, focusing on appropriate targets in the setting of alteplase administration, mechanical thrombectomy, and hemorrhagic transformation. © 2020 Wolters Kluwer Health, Inc. All rights reserved.