21st Century Evidence: Randomized Controlled Trials Versus Systematic Reviews and Meta-Analyses Agarwal, Ankita; Rochwerg, Bram; Sevransky, Jonathan E. Agarwal, Ankita; Rochwerg, Bram; Sevransky, Jonathan E. Less Critical Care Medicine. 49(12):2001-2002, December 2021. Favorite PDF Permissions Buy
Advances in Neonatal Critical Care: Pushing at the Boundaries and Connecting to Long-Term Outcomes Biban, Paolo; Marlow, Neil; te Pas, Arjan B.; More Biban, Paolo; Marlow, Neil; te Pas, Arjan B.; Fanaroff, Avroy A.; Jobe, Alan Hall Less Critical Care Medicine. 49(12):2003-2016, December 2021. Favorite PDF Permissions Buy
The Society of Critical Care Medicine at 50 Years: Interprofessional Practice in Critical Care: Looking Back and Forging Ahead Kleinpell, Ruth; Grabenkort, W. Robert; Boyle, Walter A. III; More Kleinpell, Ruth; Grabenkort, W. Robert; Boyle, Walter A. III; Vines, David L.; Olsen, Keith M. Less Critical Care Medicine. 49(12):2017-2032, December 2021. Favorite PDF Permissions Open
The Impact of Strict Public Health Restrictions on Pediatric Critical Illness* Maddux, Aline B.; Campbell, Kristen; Woodruff, Alan G.; More Maddux, Aline B.; Campbell, Kristen; Woodruff, Alan G.; LaVelle, Jaime; Lutmer, Jeffrey; Kennedy, Curt E.; Malakooti, Marcelo; McGuire, John K.; Shekerdemian, Lara; Harris, Z. Leah; McCrory, Michael C.; Carpenter, Todd C. Less Critical Care Medicine. 49(12):2033-2041, December 2021. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Free SDC
Coronavirus Disease 2019 as Cause of Viral Sepsis: A Systematic Review and Meta-Analysis* Karakike, Eleni; Giamarellos-Bourboulis, Evangelos J.; Kyprianou, Miltiades; More Karakike, Eleni; Giamarellos-Bourboulis, Evangelos J.; Kyprianou, Miltiades; Fleischmann-Struzek, Carolin; Pletz, Mathias W.; Netea, Mihai G.; Reinhart, Konrad; Kyriazopoulou, Evdoxia Less Critical Care Medicine. 49(12):2042-2057, December 2021. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Free SDC
Sepsis Among Medicare Beneficiaries: 4. Precoronavirus Disease 2019 Update January 2012–February 2020 Frank, Charles E.; Buchman, Timothy G.; Simpson, Steven Q.; More Frank, Charles E.; Buchman, Timothy G.; Simpson, Steven Q.; Sciarretta, Kimberly L.; Plopper, George E.; Finne, Kristen P.; Sowers, Nicole; Collier, Michael; Chavan, Saurabh; Lin, Cheng; Oke, Ibijoke; Rhodes, Kiersten E.; Santhosh, Aathira; Chu, Steve; MaCurdy, Thomas E.; Patel, Sandeep A.; Disbrow, Gary L.; Kelman, Jeffrey A. Less Critical Care Medicine. 49(12):2058-2069, December 2021. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
Association Between an Increase in Serum Sodium and In-Hospital Mortality in Critically Ill Patients* Grim, Chloe C. A.; Termorshuizen, Fabian; Bosman, Robert J.; More Grim, Chloe C. A.; Termorshuizen, Fabian; Bosman, Robert J.; Cremer, Olaf L.; Meinders, Arend Jan; Nijsten, Maarten W. N.; Pickkers, Peter; de Man, Angelique M. E.; Schultz, Marcus J.; van Vliet, Peter; Weigel, Joachim D.; Helmerhorst, Hendrik J. F.; de Keizer, Nicolette F.; de Jonge, Evert Less Critical Care Medicine. 49(12):2070-2079, December 2021. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
Discordances Between Factors Associated With Withholding Extubation and Extubation Failure After a Successful Spontaneous Breathing Trial* Taran, Shaurya; Angriman, Federico; Pinto, Ruxandra; More Taran, Shaurya; Angriman, Federico; Pinto, Ruxandra; Ferreyro, Bruno L.; Amaral, Andre Carlos Kajdacsy-Balla Less Critical Care Medicine. 49(12):2080-2089, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Discordance Between Respiratory Drive and Sedation Depth in Critically Ill Patients Receiving Mechanical Ventilation* Dzierba, Amy L.; Khalil, Anas M.; Derry, Katrina L.; More Dzierba, Amy L.; Khalil, Anas M.; Derry, Katrina L.; Madahar, Purnema; Beitler, Jeremy R. Less Critical Care Medicine. 49(12):2090-2101, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Epidemiology, Outcomes, and Trends of Patients With Sepsis and Opioid-Related Hospitalizations in U.S. Hospitals* Alrawashdeh, Mohammad; Klompas, Michael; Kimmel, Simeon; More Alrawashdeh, Mohammad; Klompas, Michael; Kimmel, Simeon; Larochelle, Marc R.; Gokhale, Runa H.; Dantes, Raymund B.; Hoots, Brooke; Hatfield, Kelly M.; Reddy, Sujan C.; Fiore, Anthony E.; Septimus, Edward J.; Kadri, Sameer S.; Poland, Russell; Sands, Kenneth; Rhee, Chanu Less Critical Care Medicine. 49(12):2102-2111, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis* Assouline, Benjamin; Faivre, Anna; Verissimo, Thomas; More Assouline, Benjamin; Faivre, Anna; Verissimo, Thomas; Sangla, Frédéric; Berchtold, Lena; Giraud, Raphaël; Bendjelid, Karim; Sgardello, Sebastian; Elia, Nadia; Pugin, Jérôme; de Seigneux, Sophie; Legouis, David Less Critical Care Medicine. 49(12):2112-2120, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Effect of IV High-Dose Vitamin C on Mortality in Patients With Sepsis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials* Sato, Ryota; Hasegawa, Daisuke; Prasitlumkum, Narut; More Sato, Ryota; Hasegawa, Daisuke; Prasitlumkum, Narut; Ueoka, Miki; Nishida, Kazuki; Takahashi, Kunihiko; Nasu, Michitaka; Dugar, Siddharth Less Critical Care Medicine. 49(12):2121-2130, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients* Vassiliou, Alice G.; Athanasiou, Nikolaos; Keskinidou, Chrysi; More Vassiliou, Alice G.; Athanasiou, Nikolaos; Keskinidou, Chrysi; Jahaj, Edison; Tsipilis, Stamatios; Zacharis, Alexandros; Botoula, Efthimia; Diamantopoulos, Aristidis; Ilias, Ioannis; Vassiliadi, Dimitra A.; Tsagarakis, Stylianos; Kotanidou, Anastasia; Dimopoulou, Ioanna Less Critical Care Medicine. 49(12):2131-2136, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Fundamentally Changing Pediatric Respiratory Illnesses…and Less “Bread and Butter”* Mariscalco, M. Michele Mariscalco, M. Michele Less Critical Care Medicine. 49(12):2137-2140, December 2021. Favorite PDF Permissions Buy
Quantifying the Burden of Viral Sepsis During the Coronavirus Disease 2019 Pandemic and Beyond* Shappell, Claire N.; Klompas, Michael; Rhee, Chanu Shappell, Claire N.; Klompas, Michael; Rhee, Chanu Less Critical Care Medicine. 49(12):2140-2143, December 2021. Favorite PDF Permissions Free
Sodium Rising: Deciphering the Code* Serrano, Nicolás Serrano, Nicolás Less Critical Care Medicine. 49(12):2143-2145, December 2021. Favorite PDF Permissions Buy
Time to AIR OUT the Bias From Extubation Decision-Making* Santa Cruz Mercado, Laura A.; Bittner, Edward A. Santa Cruz Mercado, Laura A.; Bittner, Edward A. Less Critical Care Medicine. 49(12):2146-2149, December 2021. Favorite PDF Permissions Buy
Managing Patient-Ventilator Dyssynchrony* MacIntyre, Neil MacIntyre, Neil Less Critical Care Medicine. 49(12):2149-2151, December 2021. Favorite PDF Permissions Buy
Sepsis and the Opioid Crisis: Integrating Treatment for Two Public Health Emergencies* Kimball, Sarah L.; Levy, Mitchell M. Kimball, Sarah L.; Levy, Mitchell M. Less Critical Care Medicine. 49(12):2151-2153, December 2021. Favorite PDF Permissions Buy
Orange You Wishing There Were Definitive Randomized Controlled Trials Already?* Hager, David N.; Agarwal, Ankita; Rochwerg, Bram Hager, David N.; Agarwal, Ankita; Rochwerg, Bram Less Critical Care Medicine. 49(12):2154-2157, December 2021. Favorite PDF Permissions Buy
Glucocorticoid-Glucocorticoid Receptor Response to Severe Acute Respiratory Syndrome Coronavirus 2* Annane, Djillali; Godot, Véronique Annane, Djillali; Godot, Véronique Less Critical Care Medicine. 49(12):2157-2160, December 2021. Favorite PDF Permissions Buy
Severe COVID-19 and Stroke—Another Piece in the Puzzle* Robinson, Christopher P.; Busl, Katharina M. Robinson, Christopher P.; Busl, Katharina M. Less Critical Care Medicine. 49(12):2160-2164, December 2021. Favorite PDF Permissions Buy
Bronchiolitis and Noninvasive Ventilation. Once Again Time to Review…* Argent, Andrew C. Argent, Andrew C. Less Critical Care Medicine. 49(12):2164-2166, December 2021. Favorite PDF Permissions Buy
A Locally Optimized Data-Driven Tool to Predict Sepsis-Associated Vasopressor Use in the ICU Holder, Andre L.; Shashikumar, Supreeth P.; Wardi, Gabriel; More Holder, Andre L.; Shashikumar, Supreeth P.; Wardi, Gabriel; Buchman, Timothy G.; Nemati, Shamim Less Critical Care Medicine. 49(12):e1196-e1205, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Prevalence and Clinical Impact of Reduced Coagulation Factor XII Activity in Patients Receiving Extracorporeal Membrane Oxygenation Buchtele, Nina; Schwameis, Michael; Schellongowski, Peter; More Buchtele, Nina; Schwameis, Michael; Schellongowski, Peter; Quehenberger, Peter; Knöbl, Paul; Traby, Ludwig; Schmid, Monika; Schoergenhofer, Christian; Herkner, Harald; Jilma, Bernd; Staudinger, Thomas Less Critical Care Medicine. 49(12):e1206-e1211, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Automated Assessment of Brain CT After Cardiac Arrest—An Observational Derivation/Validation Cohort Study Kenda, Martin; Scheel, Michael; Kemmling, André; More Kenda, Martin; Scheel, Michael; Kemmling, André; Aalberts, Noelle; Guettler, Christopher; Streitberger, Kaspar J.; Storm, Christian; Ploner, Christoph J.; Leithner, Christoph Less Critical Care Medicine. 49(12):e1212-e1222, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Ischemic and Hemorrhagic Stroke Among Critically Ill Patients With Coronavirus Disease 2019: An International Multicenter Coronavirus Disease 2019 Critical Care Consortium Study* Cho, Sung-Min; Premraj, Lavienraj; Fanning, Jonathon; More Cho, Sung-Min; Premraj, Lavienraj; Fanning, Jonathon; Huth, Samuel; Barnett, Adrian; Whitman, Glenn; Arora, Rakesh C.; Battaglini, Denise; Porto, Diego Bastos; Choi, HuiMahn; Suen, Jacky; Bassi, Gianluigi Li; Fraser, John F.; Robba, Chiara; Griffee, Matthew Less Critical Care Medicine. 49(12):e1223-e1233, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Noninvasive Ventilation and Outcomes in Bronchiolitis* Shanahan, Kristen H.; Monuteaux, Michael C.; Nagler, Joshua; More Shanahan, Kristen H.; Monuteaux, Michael C.; Nagler, Joshua; Bachur, Richard G. Less Critical Care Medicine. 49(12):e1234-e1240, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Prediction of Postictal Delirium Following Status Epilepticus in the ICU: First Insights of an Observational Cohort Study Baumann, Sira M.; Semmlack, Saskia; Hunziker, Sabina; More Baumann, Sira M.; Semmlack, Saskia; Hunziker, Sabina; Kaplan, Peter W.; De Marchis, Gian Marco; Rüegg, Stephan; Marsch, Stephan; Sutter, Raoul Less Critical Care Medicine. 49(12):e1241-e1251, December 2021. Abstract Abstract Favorite PDF Permissions Buy
A Core Outcome Set for Research in Patients on Extracorporeal Membrane Oxygenation Hodgson, Carol L.; Fulcher, Bentley; Mariajoseph, Frederick P.; More Hodgson, Carol L.; Fulcher, Bentley; Mariajoseph, Frederick P.; Burrell, Aidan J. C.; Pellegrino, Vincent; Brodie, Daniel; Fan, Eddy Less Critical Care Medicine. 49(12):e1252-e1254, December 2021. Abstract Abstract Favorite PDF Permissions Buy SDC
Procalcitonin as a Mediator in Sepsis: Are We Reinventing the Wheel? Honore, Patrick M.; Redant, Sebastien; Preseau, Thierry; More Honore, Patrick M.; Redant, Sebastien; Preseau, Thierry; Kaefer, Keitiane; Barreto Gutierrez, Leonel; Attou, Rachid; Gallerani, Andrea; De Bels, David Less Critical Care Medicine. 49(12):e1255-e1256, December 2021. Favorite PDF Permissions Buy
The authors reply Baranowsky, Anke; Keller, Johannes Baranowsky, Anke; Keller, Johannes Less Critical Care Medicine. 49(12):e1256-e1257, December 2021. Favorite PDF Permissions Buy
Use of Corticosteroids During Intra- or Out-of-Hospital Cardiac Arrests: Not Without Concomitant Use of Vasopressin and Epinephrine. We Should Not Mix Intra- and Out-of-Hospital Cardiac Arrests! Honore, Patrick M.; Redant, Sebastien; Preseau, Thierry; More Honore, Patrick M.; Redant, Sebastien; Preseau, Thierry; Kaefer, Keitiane; Barreto Gutierrez, Leonel; Attou, Rachid; Gallerani, Andrea; De Bels, David Less Critical Care Medicine. 49(12):e1258-e1259, December 2021. Favorite PDF Permissions Buy
The authors reply Shah, Kieran; Mitra, Anish R. Shah, Kieran; Mitra, Anish R. Less Critical Care Medicine. 49(12):e1259-e1260, December 2021. Favorite PDF Permissions Buy
Higher Than Expected Severity-Adjusted Mortality in ICU Patients With Coronavirus Disease 2019: Time to Consider the Contributions of Pandemic-Related Transformations in Structure and Process Oud, Lavi Oud, Lavi Less Critical Care Medicine. 49(12):e1260-e1261, December 2021. Favorite PDF Permissions Buy
The authors reply Higgins, Thomas L.; Stark, Maureen M.; Henson, Kathy; More Higgins, Thomas L.; Stark, Maureen M.; Henson, Kathy; Freeseman-Freeman, Laura Less Critical Care Medicine. 49(12):e1262, December 2021. Favorite PDF Permissions Buy
Improve the Quality of Reporting to Improve Scientific Knowledge in the Field of Extracorporeal Membrane Oxygenation Schweizer, Rémi; Jacquet-Lagreze, Matthias; Portran, Philippe; More Schweizer, Rémi; Jacquet-Lagreze, Matthias; Portran, Philippe; Riad, Zakaria; Pozzi, Matteo; Fellahi, Jean-Luc Less Critical Care Medicine. 49(12):e1263-e1264, December 2021. Favorite PDF Permissions Buy
The authors reply Scott, John Harwood; Rali, Parth Scott, John Harwood; Rali, Parth Less Critical Care Medicine. 49(12):e1264-e1265, December 2021. Favorite PDF Permissions Buy
Influenza-Associated Pulmonary Aspergillosis: Seek, and You Shall Find! Feys, Simon R. L.; Shoham, Shmuel; Rijnders, Bart J. A.; More Feys, Simon R. L.; Shoham, Shmuel; Rijnders, Bart J. A.; Wauters, Joost Less Critical Care Medicine. 49(12):e1265-e1266, December 2021. Favorite PDF Permissions Buy
The authors reply Coste, Anne; Aubron, Cécile Coste, Anne; Aubron, Cécile Less Critical Care Medicine. 49(12):e1267-e1268, December 2021. Favorite PDF Permissions Buy
Motoric Subtypes of Delirium: Not Associated With Long-Term Outcomes in Adults After Critical Illness? Gao, Rui; Zhao, Zhehao; Chen, Chan Gao, Rui; Zhao, Zhehao; Chen, Chan Less Critical Care Medicine. 49(12):e1268-e1269, December 2021. Favorite PDF Permissions Buy
The authors reply Rengel, Kimberly F.; Shotwell, Matthew S.; Hughes, Christopher G. Rengel, Kimberly F.; Shotwell, Matthew S.; Hughes, Christopher G. Less Critical Care Medicine. 49(12):e1269-e1270, December 2021. Favorite PDF Permissions Buy
The Limitations of Standardized Mortality Ratios for Coronavirus Disease 2019 ICU Patients Quintairos, Amanda; Zampieri, Fernando G.; Souza-Dantas, Vicente Cés; More Quintairos, Amanda; Zampieri, Fernando G.; Souza-Dantas, Vicente Cés; Salluh, Jorge I. F. Less Critical Care Medicine. 49(12):e1270-e1271, December 2021. Favorite PDF Permissions Buy
The authors reply Higgins, Thomas L.; Freeseman-Friedman, Laura; Henson, Kathy N.; More Higgins, Thomas L.; Freeseman-Friedman, Laura; Henson, Kathy N.; Ringle, Eric Less Critical Care Medicine. 49(12):e1272-e1273, December 2021. Favorite PDF Permissions Buy
Implication of Early Impella Support in Postcardiac Arrest Cardiogenic Shock Complicating Acute Myocardial Infarction Hiroi, Shunta; Imamura, Teruhiko Hiroi, Shunta; Imamura, Teruhiko Less Critical Care Medicine. 49(12):e1274, December 2021. Favorite PDF Permissions Buy
The authors reply Chatzis, Georgios; Syntila, Styliani; Schieffer, Bernhard; More Chatzis, Georgios; Syntila, Styliani; Schieffer, Bernhard; Karatolios, Konstantinos Less Critical Care Medicine. 49(12):e1275-e1276, December 2021. Favorite PDF Permissions Buy
Improved Survival Through Early Versus Late Impella Support for Myocardial Infarction–Related Shock? Mind Your Step! Meuwese, Christiaan L.; Pladet, Claartje L. A.; Kraaijeveld, Adriaan O.; More Meuwese, Christiaan L.; Pladet, Claartje L. A.; Kraaijeveld, Adriaan O.; Donker, Dirk W. Less Critical Care Medicine. 49(12):e1276-e1277, December 2021. Favorite PDF Permissions Buy
The authors reply Chatzis, Georgios; Syntila, Styliani; Schieffer, Bernhard; More Chatzis, Georgios; Syntila, Styliani; Schieffer, Bernhard; Karatolios, Konstantinos Less Critical Care Medicine. 49(12):e1277-e1278, December 2021. Favorite PDF Permissions Buy
A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients With Coronavirus Disease 2019: Erratum Less Critical Care Medicine. 49(12):e1279, December 2021. Favorite PDF Permissions Buy Erratum
Trends in 28-Day Mortality of Critical Care Patients With Coronavirus Disease 2019 in the United Kingdom: A National Cohort Study, March 2020 to January 2021: Erratum Less Critical Care Medicine. 49(12):e1279, December 2021. Favorite PDF Permissions Buy Erratum