1 Department of Pediatrics, Children’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada.
2 Pediatric and Neonatal ICU, University Children`s Hospital Zurich, Zurich, Switzerland, and Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.
3 KEMRI Wellcome Trust Research Program, Nairobi, Kenya.
4 Department of Paediatrics and Child Health, Red Cross War Memorial Children’s Hospital and University of Cape Town, Cape Town, South Africa.
5 Department of Paediatrics, Verona University Hospital, Verona, Italy.
6 Department of Clinical Infection Microbiology and Immunology, University of Liverpool Institute of Infection, Veterinary and Ecological Sciences, Liverpool, United Kingdom.
7 Children’s Hospital of Philadelphia, Philadelphia, PA.
8 International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
9 Department of Critical Care Medicine, University of Pittsburgh School of Medicine, and The Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Pittsburgh, PA.
10 Paediatric Intensive Care Unit, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
11 Departments of Emergency Medicine and Pediatrics, University of California San Diego School of Medicine, La Jolla, CA.
12 Department of Pediatrics, University of British Columbia and British Columbia Children’s Hospital, Vancouver, BC, Canada.
13 All India Institute of Medical Sciences, Delhi, India.
14 St. Mary’s Hospital, Imperial College Healthcare NHS Trust, and Imperial College London, London, United Kingdom.
15 Associação de Medicina Intensiva Brasileira, São Paulo, Brazil.
16 University College London Great Ormond Street Institute of Child Health, London, United Kingdom.
17 Departments of Anesthesia and Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
18 Departments of Pediatrics and Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
19 Departments of Pediatrics, Hospital Sírio-Libanês and Hospital Universitário da Universidade de São Paulo, São Paolo, Brazil.
20 Pediatric Intensive Care, AP-HP Paris Saclay University, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
21 Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA.
22 University of British Columbia, Vancouver, BC, Canada.
23 Mbarara University of Science and Technology, Mbarara, Uganda.
24 Department of Pediatrics, University of Florida, Gainesville, FL.
25 Ann & Robert H. Lurie Children’s Hospital and Department of Pediatrics, Northwestern University Feinberg School of Medicine, Lurie Children’s Pediatric Research & Evidence Synthesis Center (PRECIISE): A JBI Affiliated Group, Chicago, IL.
*See also p. 148.
Members of the Pediatric Sepsis Definition Taskforce of the Society of Critical Care Medicine are listed in the Acknowledgments.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/ccmjournal).
Supported, in part, by the Society of Critical Care Medicine and a Tier 2 Clinical Research Chair of the University of Ottawa, Faculty of Medicine, Ottawa, Canada.
Dr. Menon has a Canadian Institutes of Health Research grant for the study of corticosteroids in pediatric septic shock. Dr. Menon’s institution received funding from Crowdsourcing; he disclosed that he is a principal investigator on an international trial on Steroids in Pediatric Sepsis Shock. Drs. Menon and Watson received funding from Society of Critical Care Medicine. Dr. Argent received funding from the World Federation of Pediatric Intensive and Critical Care Societies as a part of the process of working with the Pediatric Sepsis Definitions working group. Dr. Biban received funding from Chiesi and Getinge. Dr. Nadel received funding from Abbvie. Dr. Sadeghirad received funding from the Pre-Interventional Preventative Risk Assessment AG, Mitacs Canada, and Accelerate internship in partnership with Nestlé Canada. Dr. Scott’s institution received funding from the Agency for Healthcare Research and Quality (AHRQ K08HS025696); he received support for article research from the AHRQ. Dr. Tissieres received funding from Sedana, Inotrem, and Baxter. Dr. Wynn received funding from the National Institutes of Health (NIH) (R01GM128452; R01HD089939, R01HD097081, R43EB029863). Dr. Zimmerman’s institution received funding from the NIH, the National Institute of Child Health and Human Development, and Immunexpress; he received funding from Elsevier Publishing. The remaining authors have disclosed that they do not have any potential conflicts of interest.
The work was coordinated at the Children’s Hospital of Eastern Ontario, Ottawa, ON K1H 8L1.
Address requests for reprints to: Kusum Menon, MD, MSc, Rm 3446, Children’s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON K1H 8L1, Canada. E-mail: [email protected]
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