1 Intensive Care Unit, Wellington Hospital, Wellington, New Zealand.
2 Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, VIC, Australia.
3 University of Melbourne, Parkville, VIC, Australia.
4 Monash University, School of Clinical Sciences, Clayton, VIC, Australia.
5 Data Analytics Research and Evaluation Centre, Austin Hospital and University of Melbourne, Melbourne, VIC, Australia.
6 Department of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
7 Intensive Care Unit, Austin Hospital, Heidelberg, VIC, Australia.
8 Intensive Care, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
9 Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil.
10 Intensive Care Unit, Royal Melbourne Hospital, Parkville, VIC, Australia.
11 Medical Research Institute of New Zealand, Wellington, New Zealand.
12 Intensive Care Unit, Monash Medical Centre, Clayton, VIC, Australia.
13 University of New South Wales, Prince of Wales Clinical School of Medicine, Randwick, NSW, Australia.
*See also p. 1205.
A complete list of investigators is provided in the Electronic Supplementary Appendix (https://links.lww.com/CCM/G208).
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/ccmjournal).
Supported, in part, by The National Health and Medical Research Council of Australia and the Health Research Council of New Zealand funded in the Sedation Practice in Intensive Care Evaluation (SPICE III) study in the centers that provided data for this analysis. No funding was provided for this substudy, which was funded by institutional funds; SPICE III ClinicalTrials.gov number, NCT01728558.
Dr. Grayson received funding from institutional funds. Dr. Bellomo reports receiving fees for expert testimony from Pfizer. Dr. Wright’s institution received funding from the Cardiothoracic Research Fund and the Sydney Medical School Foundation- University of Sydney, Australia. Dr. Shehabi's institution received funding from Orion Pharma; he received funding from Monach Health (lecture fees and travel support), Pfizer (lecture fees), and from Stephens Lawyers and Consultants, Melbourne, Australia (expert testimony); and he received support for article research from the Australian National Health and Medical Research Council. The remaining authors have disclosed that they do not have any potential conflicts of interest.
A post hoc analysis of a nested cohort within “The Sedation Practice in Intensive Care Evaluation [SPICE] III” randomized controlled trial.
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