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Should Patients With Acute Respiratory Distress Syndrome on Venovenous Extracorporeal Membrane Oxygenation Have Ventilatory Support Reduced to the Lowest Tolerable Settings? Yes

Zakhary, Bishoy MD1; Fan, Eddy MD, PhD2,3; Slutsky, Arthur CM, FRSC, MD3,4

doi: 10.1097/CCM.0000000000003835

1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Oregon Health and Science University, Portland, OR.

2Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.

3Division of Respirology, Department of Medicine, University Health Network and Sinai Health System, Toronto, ON, Canada.

4Keenan Research Center, Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, ON, Canada.

Dr. Zakhary disclosed off-label product use of extracorporeal membrane oxygenation for respiratory failure. Dr. Fan received funding from MC3 Cardiopulmonary and ALung Technologies, and he is supported by a New Investigator Award from the Canadian Institutes of Health Research. Dr. Slutsky received funding from Maquet Critical Care, Novalung, and Baxter.

Address requests for reprints to: Bishoy Zakhary, MD, Division of Pulmonary and Critical Care Medicine, Department of Medicine, 3181 SW Sam Jackson Park Rd UHN67, Portland, OR 97239-3098. E-mail:

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