Department of Medicine, Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD

*See also p. 335.

In this editorial, Dr. Cross states that vaccines and monoclonal antibodies directed at endotoxin are under development (by him and many others), but he does not endorse any one of the endotoxin-directed therapies discussed.

Dr. Cross has disclosed past and present funding from the National Institutes of Health to develop vaccines for Gram-negative bacteria.