To assess whether the triage model Sepsis
Alert for Emergency Departments results in improved initial care of patients with severe infections.
Interventional study comparing patient care before and after the start of a new triage model
, including 90-day follow-up.
Eight emergency departments in Skåne County, Sweden.
Patients with suspected severe infection.
Patients with severely deviating vital signs and suspected infection were triaged into a designated sepsis
line called Sepsis
Alert, for rapid evaluation supported by an infectious disease specialist. Also, all emergency department
staff participated in a designated sepsis
education before the model was introduced.
Measurements and Main Results:
Medical records were evaluated for a 3-month period 1 year before the triage system was started in 2016 and for a 3-month period 1 year after. Of 195,607 patients admitted to these emergency departments during two 3-month periods, a total of 5,321 patients presented severely abnormal vital signs. Of these, 1,066 patients who presented with fever greater thanor equal to 38°C or history of fever/chills were considered to be patients at risk of having severe sepsis
. Among patients triaged according to Sepsis
Alert, 89.3% received antibiotic treatment within 1 hour after arrival to the emergency department
(median time to antibiotics
, 26 min), which was significantly better than before the start of the new triage: 67.9% (median time to antibiotics
, 37 min) (p
< 0.001). Additionally, sepsis
treatment quality markers were significantly improved after the introduction of Sepsis
Alert, including number of blood cultures and lactate measurements taken, percentage of patients receiving IV fluids, and appropriate initial antibiotic treatment. There were no differences in 28- or 90-day mortality rates.
of the new triage model Sepsis
Alert with special attention to severe sepsis
patients led to faster and more accurate antibiotic treatment and improved diagnostic procedures and supportive care.