1 Department of Intensive Care, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
2 Department of Intensive Care, Jeroen Bosch Hospital, ’s-Hertogenbosch, The Netherlands.
3 Department of Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
4 Department of Intensive Care, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
5 Department of Intensive Care, Rijnstate Hospital, Arnhem, The Netherlands.
6 Department of Anesthesiology, Intensive Care and Pain Medicine, Amphia Hospital, Breda, The Netherlands.
7 Department of Intensive Care, Bernhoven Hospital, Uden, The Netherlands.
8 Department of Intensive Care, Maas Hospital Pantein, Boxmeer, The Netherlands.
*See also p. 691.
Drs. Simons, van der Hoeven, van den Boogaard, and Zegers designed the study. Drs. Simons, Corsten, Westerhof, Rettig, Ewalds, Janssen, van der Hoeven, van den Boogaard, and Zegers contributed substantially to the acquisition of data. Dr. Porter and Mr. Ramjith performed the statistical analyses. Dr. Porter drafted the article. All other authors provided critical revisions of the article and approved the final version of the article submitted for publication.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/ccmjournal).
This study was funded by the Jeroen Bosch Hospital and Radboud University Medical Centre.
Dr. Porter disclosed that this research is funded by the Radboudumc and Jeroen Bosch Hospital through a grant called the Junior Researcher Project, and she received support for article research from Radboudumc and Jeroen Bosch Ziekenhuis. Dr. Rettig received funding from Roche Diagnostics and Cablon Medical. The remaining authors have disclosed that they do not have any potential conflicts of interest.
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