1Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Augustenburger Platz 1, D-13353 Berlin, Germany.
2Berlin Institute of Health (BIH), Berlin, Germany.
3Klinik für Innere Medizin II, Schwarzwald-Baar-Klinikum, Villingen-Schwenningen, Germany.
4Department of Hematology and Oncology, Universitätsklinikum Jena, Jena, Germany.
5Clinic of Pediatric Hematology and Oncology, University Medical Center Eppendorf, Hamburg, Germany.
6Center for Clinical Studies, Department of Anesthesiology and Intensive Care Medicine, Universitätsklinikum Jena, Jena, Germany.
*See also p. 599.
Drs. Lachmann and Knaak contributed equally to this work.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/ccmjournal).
Preliminary data of this manuscript were presented as a poster at the German Sepsis Society meeting: Sepsis Update 2019, Weimar, Germany, September 11-13, 2019.
Dr. Lachmann is a participant of the Berlin Institute of Health (BIH) Charité Clinician Scientist Program funded by the Charité – Universitätsmedizin Berlin and the BIH. Prof. Balzer’s institution received funding from Einstein Foundation and Clearflow, and he received funding from Medtronic. Prof. Spies’ institution received funding from BIH (Clinician Scientist Program). The remaining authors have disclosed that they do not have any potential conflicts of interest.
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